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Fluid Management Systems FMS
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ibidi GmbH
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Image Search Results
Journal: Brain stimulation
Article Title: Temporal interference stimulation targets deep brain regions by modulating neural oscillations
doi: 10.1016/j.brs.2020.11.007
Figure Lengend Snippet: (A) Computational current-flow model. A.1, Temporal Interference (TI) stimulation via two pairs of electrodes on scalp. Current flows between FT7 and P7 on the left and between FT8 and P8 on the right hemisphere. A.2 Spatial distribution of electric field magnitude in posterior/anterior direction across brain. A.3, Spatial distribution of amplitude-modulation across the brain in posterior/anterior direction. (B) Rodent in vitro model of gamma oscillations. B.1, Experimental setup: spatially uniform electric field was applied across hippocampal slice in an interface chamber. Recording of gamma oscillation in CA3a region relative to an iso-potential electrode in the bath. B.2 and B.3, Gamma oscillation induced by 20 μM carbachol in vitro and its stability in power and frequency. (C) Computational model of gamma oscillations. C.1, The network model has excitatory and inhibitory neurons (1050 neurons, 800 excitatory) that are sparsely connected with varied synaptic weights. C.2, Simulated gamma oscillation in the network model by averaging postsynaptic currents across the network. C.3, Raster-plot representing the firing activity of excitatory (red) and inhibitory (blue) neurons during induced gamma oscillation.
Article Snippet: After 60 min, slices were then transferred to a
Techniques: In Vitro, Activity Assay